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arg-gly-asp中文是什么意思

  • 細(xì)胞粘附肽

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  • 例句與用法
  • Pretreat of 0 . 15mmol - l - 1 rgd ( arg - gly - asp ) reduces the interaction between cell wall and plasma membrane and inhibits the stress induced - aba accumulation by 50 percent
    本實(shí)驗(yàn)結(jié)果表明:細(xì)胞壁與細(xì)胞膜之間相互作用的變化是煙草細(xì)胞對甘露醇脅迫處理的原初響應(yīng)。
  • Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells . only after adhering to surface followed by spreading can cells develop and proliferate . most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity , which may correlates to the low degree of cell attachment . modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation . cell attachment to substrate is primarily mediated by integrins , a widely expressed family of heterodimeric surface receptors . most extrcellular matrix proteins such as fibronectin , osteopontin , collagen type i , bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin . the main aim of this research is to measure , assess adhesion , proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin , collagen type i or biotie gen , which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture . ( 2 ) adhesion , proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed . ( 3 ) also , adhesion , proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin , or collagen type i respectively . ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo . this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities
    因此將這些蛋白包被、固定到材料表面,觀察骨組織工程種子細(xì)胞mscs細(xì)胞的粘附、生長特性是本研究的中心環(huán)節(jié),并從以下方面進(jìn)行探討: ( 1 )采用不同原代細(xì)胞分離方法,研究其對mscs細(xì)胞的生物學(xué)特性影響。 ( 2 )檢測基因勝肽膠對mscs細(xì)胞粘附、增殖及分化的影響。 ( 3 )分別采用型膠原及纖維粘連蛋白( fibronectin , fn )包被聚乙醇酸-乳酸共聚物( poly ( 1actide - co - glycolide ) , plga )膜及多孔塊型plga材料,觀察細(xì)胞在單層或三維培養(yǎng)狀態(tài)下,型膠原及fn對mscs細(xì)胞粘附、增殖及向成骨細(xì)胞分化效應(yīng)及能力。
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