In this case, lss-dca aligned the sequences with the same way as clustalw 在這種情況下,lss-dca的策略就不起作用,只采用clustalw對(duì)齊序列。
The protein sequence of nos from 25 difference animals was alignment use clustalw and mega software . the amino acid sequences of nos have apparent difference and have conservative property in some important domain . the variance of this molecule is correlated to the phylogeny of these animals 運(yùn)用clustalw和mega軟件對(duì)動(dòng)物界已知的25種一氧化氮合酶蛋白質(zhì)序列的比較發(fā)現(xiàn),一氧化氮合酶分子的氨基酸序列既存在明顯的分歧,同時(shí)一些重要功能區(qū)又表現(xiàn)出較高的保守性。
In recent years, it is due to the modification and improvement of the algorithms and especially the development of computer science and technology both in hardware and software that lead to the advent of such practical analytic tools as blast, fasta, clustalw, which can relatively cater for the need of research in both efficiency and accuracy . the fundamental way to improve computation efficiency and accuracy is to better the alignment algorithms in principle so as to minish the computation complexity 雖然近年來(lái)由于算法自身的不斷改進(jìn)以及計(jì)算機(jī)科學(xué)的發(fā)展,其實(shí)現(xiàn)程序依靠計(jì)算機(jī)硬件和軟件開發(fā)技術(shù)的提高得到了效率和精度上的改善,從而使現(xiàn)在應(yīng)用廣泛的序列比對(duì)或數(shù)據(jù)庫(kù)搜索程序如blast、fasta、clustalw等才獲得了相對(duì)滿意的計(jì)算效率,但是從理論基礎(chǔ)和思想原理上改善序列比對(duì)算法以期降低計(jì)算復(fù)雜度,才是提高計(jì)算效率和精度的根本途徑。