While some data suggest that epoxidation may be involved in the metabolic activation of steviol , other data indicate that the active metabolite is not an epoxide . preliminary data indicate that steviol may be activated to a mutagenic metabloite by human liver microsomes 有些數(shù)據(jù)指出,甜菊醇在代謝活化的過程中,可能牽涉環(huán)氧化作用,但其他數(shù)據(jù)顯示,甜菊醇的活性代謝物并不是環(huán)氧化物。
Mmf is the morpholinoethyl ester prodrug of its active metabolite inycophenolic acid ( mpa . mpa is a noncompetitive , reversible inhibitor of the enzyme inosine 5 ' - monophosphate dehydrogenase ( impdh ) , which plays a maor role in the de novo spohesis of guansine nucleotides Balb c和c57bl 6小鼠是純系的同種小鼠,具有不同的主要組織相容性抗原( mhc i 、 11 ) ,可進(jìn)行同種排斥反應(yīng)的兔疫學(xué)研究。