resolvin造句
例句與造句
- FLAP is necessary for the activation of 5-lipoxygenase and therefore for the production of leukotrienes, 5-hydroxyeicosatetraenoic acid, 5-oxo-eicosatetraenoic acid, and specialized pro-resolving mediators of the lipoxin and resolvin classes.
- However, the most studied and accepted role for FPR2 receptors is in mediating the actions of the cited lipoxins and resolvins in dampening and resolving a wide range of inflammatory reactions ( see lipoxin, Epi-lipoxin, and resolvin ).
- The mechanism behind the resolvin's inhibitory effects on them in not clear but may be indirect and involve at least in certain cases the activation of a GPRs located on the neruons or nearbymicroglia and / or astrocyte cells of the nerve tissue.
- Resolvin E1 ( RvE1 ), RvD2 ( see resolvins ), neuroprotectin D1 ( NPD1 ), and maresin 1 ( Mar1 ) are metabolites of the omega 3 fatty acids, eicosapentaenoic acid ( for RvE1 ) or docosahexaenoic acid ( for RvD2, NPD1, and Mar1 ).
- Resolvin D1 ( RvD1 ), a metabolite of the omega 3 fatty acid, docosahexaenoic acid, is a member of the specialized proresolving mediators ( SPMs ) class of metabolites that function to resolve diverse inflammatory reactions and diseases in animal models and, it its proposed, humans.
- It's difficult to find resolvin in a sentence. 用resolvin造句挺難的
- At least 6 members of the D series of resolvins ( RvDs ) viz ., RvD1, RvD2m AT-RVD1, RvD3, AT-RvD3, and RvD5, activate their target cells through this receptor; these results have led to naming GPR32 the RVD1 receptor ( see Resolvin # Mechanisms of Action ).
- Resolvin D2 ( RvD2 ), a member of the specialized proresolving mediators ( SPM ) class of polyunsaturated fatty acid metabolites, is an activating ligand for GPR18; RvD2 and its activation of GPR18 contribute to the resolution of inflammatory responses as well as inflammation-based and other diseases in animal models and are proposed to do so in humans.
- A major function for FPR2 is binding certain specialized pro-resolving mediators ( SPMs ), i . e . lipoxin ( Lx ) A4, and AT-LxA4 ( metabolites of arachidonic acid ) as well as resolvin D1 ( ReVD ) 1, ReVD2, and AT-RevD1 ( metabolites of docosahexaenoic acid ) and thereby to mediate these metabolites activities in inhibiting and resolving inflammation ( see Specialized pro-resolving mediators ).
- *Resolvin Ds ( RvDs ), i . e . RvD-1, RvD2, RvD3, RvD4, RvD5, and RvD6 ( see resolvin and specialized proresolving mediators # DHA-derived Resolvins ) and protetin Ds ( PDs ), i . e . PD1, PDX, 20-hydroxy-PD1, 17-epi-PD1, and 10-epi-PD1 ( see neuroprotectin D1 and specialized proresolving mediators # DHA-derived protectins / neuroprotectins ).
- *Resolvin Ds ( RvDs ), i . e . RvD-1, RvD2, RvD3, RvD4, RvD5, and RvD6 ( see resolvin and specialized proresolving mediators # DHA-derived Resolvins ) and protetin Ds ( PDs ), i . e . PD1, PDX, 20-hydroxy-PD1, 17-epi-PD1, and 10-epi-PD1 ( see neuroprotectin D1 and specialized proresolving mediators # DHA-derived protectins / neuroprotectins ).
- Specialized pro-resolving mediators are cell-derived metabolites of certain polyunsaturated fatty acids viz . : arachidonic acid which is metabolized to the lipoxins; eicosapentaenoic acid which is metabolized to the Resolvin E's; docosahexaenoic acid which is metablized to the Resolvin D's, Maresins, and Neuroprotectins; and n-3 docosapentaenoic acid which is metabolized to the n-3 docosapentaenoic acid-derived resolvins and n-3 docosapentaenoic acid-derived neuroprotectins ( See Specialized pro-resolving mediators ).
- Specialized pro-resolving mediators are cell-derived metabolites of certain polyunsaturated fatty acids viz . : arachidonic acid which is metabolized to the lipoxins; eicosapentaenoic acid which is metabolized to the Resolvin E's; docosahexaenoic acid which is metablized to the Resolvin D's, Maresins, and Neuroprotectins; and n-3 docosapentaenoic acid which is metabolized to the n-3 docosapentaenoic acid-derived resolvins and n-3 docosapentaenoic acid-derived neuroprotectins ( See Specialized pro-resolving mediators ).
- For example, ALOX5 and ALOX15 or, alternatively, ALOX5 and ALOX12 can act serially to metabolize arachidonic acid into lipoxins ( see 15-hydroxyicosatetraenoic acid # Further metabolism of 15 ( S )-HpETE, 15 ( S )-HETE, 15 ( R )-HpETE, 15 ( R )-HETE, and 15-oxo-ETE and lipoxin # Biosynthesis ) while ALOX15 and possibly ALOX15B can act with ALOX5 to metabolize eicosapentaenoic acid to resolvin D's ( see resolvin # Production ).
- For example, ALOX5 and ALOX15 or, alternatively, ALOX5 and ALOX12 can act serially to metabolize arachidonic acid into lipoxins ( see 15-hydroxyicosatetraenoic acid # Further metabolism of 15 ( S )-HpETE, 15 ( S )-HETE, 15 ( R )-HpETE, 15 ( R )-HETE, and 15-oxo-ETE and lipoxin # Biosynthesis ) while ALOX15 and possibly ALOX15B can act with ALOX5 to metabolize eicosapentaenoic acid to resolvin D's ( see resolvin # Production ).
- FPR2 is also known as the LXA4 or ALX / FPR2 receptor based on studies finding that is a high affinity receptor for the arachidonic acid metabolite, lipoxin A4 ( LXA4 ), and thereafter for a related arachidonic acid metabolite, the Epi-lipoxin, aspirin-triggered lipoxin A4 ( i . e . ATL, 15-epi-LXA4 ) and a docosahexaenoic acid metabolite, resolvin D1 ( i . e . RvD1 ); these three cell-derived fatty acid metabolites act to inhibit and resolve inflammatory responses.
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