2 if doses sufficient to cause paralysis are administered to animals , then anaesthesia and artificial entilation will also be required , which may exert their own effects and so risk obscuring any toxic action 強(qiáng)效神經(jīng)肌肉阻斷劑的毒性試驗(yàn)代表了一種平衡,即在物質(zhì)藥理作用增強(qiáng)的實(shí)驗(yàn)性局限性和毒理學(xué)家想要用盡可能大的劑量以發(fā)現(xiàn)該物質(zhì)任何潛在的能引起不合需要的反應(yīng)之間的平衡。