hap1造句
例句與造句
- The new protein was named HAP1, for huntingtin associated protein 1.
- The function of HAP1 is not known, Ross said.
- HAP1 preferentially interacts with muHtt in a polyQ dependent manner.
- The subcellular location of HAP1 closely resembles that of Htt.
- Cells in those regions may be especially vulnerable to whatever it is that HAP1 and mutant huntingtin do together.
- It's difficult to find hap1 in a sentence. 用hap1造句挺難的
- HAP1 is found in areas of the brain known to be affected in Huntington's disease, Ross said.
- HAP1 also interacts with proteins other than Htt and it is likely that their function is altered in HD pathogenesis.
- More importantly, HAP1 may also disrupt endocytosis, as it has been detected on vesicles involved in the early stages of this process.
- It is possible that the non-pathogenic activity of HAP1 is intracellular trafficking and that this is perturbed following its association with mHtt.
- They did not find HAP1 labeling in protein aggregates in the cytoplasm and postulated that this indicated HAP1 in pre-aggregate related HD pathogenesis.
- They did not find HAP1 labeling in protein aggregates in the cytoplasm and postulated that this indicated HAP1 in pre-aggregate related HD pathogenesis.
- The possible significance of this interaction is that increased HAP1 interaction with muHtt may also increase nitric oxide ( NO ) thus facilitating neuronal damage.
- The nice part of this work is that the same assay that found HAP1 binding to huntingtin could be used to screen drugs, Ross said.
- The role of HAP1 in HD pathogenesis may involve aberration of cell cycle processes, as high immunostaining of HAP1 during the cell cycle has been observed.
- The role of HAP1 in HD pathogenesis may involve aberration of cell cycle processes, as high immunostaining of HAP1 during the cell cycle has been observed.
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