Swine pox, which belongs to the pox disease complex, is caused by two antigenically different poxviruses . 豬痘屬于痘病群,是由兩種抗原上不同的痘病毒引起的。
The results suggested that human hscs can engraft into rat and differentiate into multilineage under certain microenvironment . thus , the human / rat xenograft model may provide a useful and convenient method for assay human hscs in vivo 新生大鼠免疫系統(tǒng)發(fā)育不完善,對(duì)異種抗原可形成免疫耐受,是很好的研究異種移植的實(shí)驗(yàn)動(dòng)物,且經(jīng)濟(jì)。
Three types of influenza viruses are recognized : a , b and c . influenza a viruses are further categorized into subtypes on the basis of two surface antigens : haemagglutinin and neuraminidase 流感病毒共分甲乙丙型三種。甲型流感可依據(jù)病毒表面的血凝素haemagglutinin ,即h及神經(jīng)胺酸neuraminidase ,即n兩種抗原類型,再細(xì)分為不同的亞型。
Three types of influenza viruses are recognised : a , b and c . influenza a viruses are further categorised into subtypes on the basis of two surfaces antigens : haemagglutinin and neuraminidase 流感病毒共分甲乙丙型三種。甲型流感可依據(jù)病毒表面的血凝素haemagglutinin ,即h及神經(jīng)胺酸neuraminidase ,即n兩種抗原類型,再細(xì)分為不同的亞型。
A protein substance produced in the blood or tissues in response to a specific antigen , such as a bacterium or a toxin . antibodies destroy or weaken bacteria and neutralize organic poisons , thus forming the basis of immunity 抗體,免疫體血液或組織針對(duì)某種抗原如細(xì)菌或毒素而產(chǎn)生的蛋白質(zhì)物質(zhì)。抗體消滅細(xì)菌或削弱其作用,中和有機(jī)毒素,因而形成免疫力
On the consideration of these problems and the fact that the rat immune system is not fully developed until birth , we tried to transplant neonatal rat with human hscs to test the possibility of this xenograft model 但此實(shí)驗(yàn)?zāi)P筒僮鲝?fù)雜且實(shí)驗(yàn)周期長,大多數(shù)實(shí)驗(yàn)室不具備利用此實(shí)驗(yàn)?zāi)P偷臈l件。有研究證明,新生大鼠免疫系統(tǒng)發(fā)育不完善,對(duì)異種抗原可形成免疫耐受。
The acellular matrix treated by sds or glutaraldehyde should be cleaned by normal saline , or there will be cytotoxicity in it . the results of cell culture and implantation experiment demonstrate the high degree of cytocompatibibity and biocompatibility of this kind of acelluler matrix A半乳糖殘基是豬到人的主要異種抗原,會(huì)導(dǎo)致超急性免疫排斥,要實(shí)現(xiàn)豬到人的異種移植首先要去除的就是o gal 。
Genetic vaccine is quite different in structure from traditional ones . the experiments show that delivery of genetic material into an animal ' s cells can trigger some synthesiztion of the encoden proteins as well as of antibodies targeted against those proteins 核酸疫苗是將編碼某種抗原蛋白的外源基因插入某種表達(dá)載體中并直接導(dǎo)入的動(dòng)物體內(nèi),表達(dá)抗原蛋白,并誘導(dǎo)宿主產(chǎn)生對(duì)該抗原蛋白免疫應(yīng)答的革命性的新型疫苗。
In one word , the methods for producing acellulace matrix have not been standardized . in this study , we want to select the best way to produce acellular matrix . we also use immunohistochemical method for detecting the magor heterogenetic antigen a - galactosyl residues ( a - gal ) in acellular matrix 并應(yīng)用免疫組化的方法檢測(cè)脫細(xì)胞后基質(zhì)的主要異種抗原,用種植實(shí)驗(yàn)觀察異種機(jī)體對(duì)脫細(xì)胞生物基質(zhì)的組織反應(yīng)倩況,另在其上種植鼠成纖維細(xì)胞以觀察脫細(xì)胞生物基質(zhì)的細(xì)胞毒性和細(xì)胞相容問題。
In this experiment three sperm proeins , sp - 10 . aeg . tmdc - iii . that were cloned and expressed by brist u . k . , immunized on rats for analysing their immunogenicity and the effects on the fertility . then using indirect immuno - fluorescein staining method , the localization of sp - 10 , tmdc - iii and aeg on human , mouse , rabbit , pig , bull sperm was observed under confocomicroscopy . the results as follows : 1 . the rats successfully produced antibody after immunization with antigens sp - 10 , aeg , tmdc - iii respective 本文用英國葛蘭素公司重組構(gòu)建表達(dá)的三種抗原蛋白sp - io , aeg , tmdc -免疫大鼠,通過elisa實(shí)驗(yàn)、免疫熒光組化實(shí)驗(yàn)、交配實(shí)驗(yàn)對(duì)它們的免疫原性、在體內(nèi)的生殖作用、精子表達(dá)部位進(jìn)行了分析,結(jié)果如下: 1